 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| n |
Activated by
small amount of thrombin
|
|
|
generated by
TF-VIIa complex
|
|
|
| n |
Activation leads
to negatively charged
|
|
|
phospholipids
being exposed on platelet surface
|
|
| n |
Forms the
platform for augmentation of
|
|
|
coagulation
|
|
|
|
n |
IXa generated
binds to platelet surface and
|
|
|
with VIIIa forms
Xase complex
|
|
|
|
n |
Xase complex
leads to generation of
|
|
|
increased
thrombin “Thrombin Burst”
|
|